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S8kPred is a method of secondary structure prediction that rely on knowledge of conformational preferences of amino acid residues in a local environment along with evolutionary information. The method predicts using conformation propensity values of 8000 tripeptide variants of 20 residues. The method can be used to predict the three-state (Q3) and eight-state (Q8) protein secondary structure. The performance result on including CB513, CASP data sets an other validation sets indicates that the proposed method employing local environment-based propensity, 400 times labelled dataset and evolutionary information, achieved satisfactory performance with an accuracy as high as 93%.

FASTA Sequence Input